IVD, Human Recombinant

IVD, Human Recombinant is available at Gentaur for Next week delivery.

Flavoenzyme which catalyzes the conversion of isovaleryl-CoA to 3-methylcrotonyl-CoA

Biomolecule/Target:

Alternates names: Isovaleryl-CoA dehydrogenase mitochondrial, ACAD2

Synonyms: Isovaleryl-CoA dehydrogenase mitochondrial, ACAD2

Background Information: IVD (Isovaleryl Coenzyme A dehydrogenase) is a mitochondrial matrix enzyme that belongs to the acyl-CoA dehydrogenase family. IVD is a homotetrameric flavoenzyme which catalyzes the conversion of isovaleryl-CoA to 3-methylcrotonyl-CoA. Defects of the IVD gene lead to ineffective isoforms that are the underlying cause of isovaleric acidemia. Recombinant human IVD protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Reconstitution Instructions:

NCBI Gene Symbol: IVD

Gene ID: 3712

NCBI Accession: P26440