Description
IL18BP, human recombinant is available at Gentaur for Next week delivery.
An inhibitor of the proinflammatory cytokine, IL18
Biomolecule/Target: IL18BP
Alternates names: Interleukin-18-binding protein, IL18BPa
Synonyms: Interleukin-18-binding protein, IL18BPa
Background Information: IL18BP functions as an inhibitor of the proinflammatory cytokine, IL18. It binds IL18, prevents the binding of IL18 to its receptor, and thus inhibits IL18-induced IFN-gamma production, resulting in reduced T-helper type 1 immune responses. This protein is constitutively expressed and secreted in mononuclear cells. Elevated level of this protein is detected in the intestinal tissues of patients with Crohn's disease. Recombinant human IL18BP protein, fused to His-tag at N-terminus, was expressed in E.coli.
Reconstitution Instructions: N/A
NCBI Gene Symbol: IL18BP
Gene ID: 10068
NCBI Accession: O95998
Additional Information
Size: |
100 μg |
Country of Manufacturing Origin: |
USA |
Country of Animal Origin: |
USA |
Gene Source: |
Human |
Recombinant: |
Yes |
Source: |
E. coli |
Purity by SDS-PAGE: |
≥90% |
Assay: |
SDS-PAGE |
Purity: |
N/A |
Assay 2: |
N/A |
Endotoxin Level: |
< 1.0 EU per 1 microgram of protein |
Activity (Specifications/test method): |
N/A |
Biological activity: |
N/A |
Results: |
N/A |
Molecular Weight: |
20 kDa (187 aa, 31-194 aa + His Tag), confirmed by MALDI-TOF. |
Storage Temperature: |
-80°C |
Shelf Life: |
12 months |
Concentration: |
1 mg/ml |
Appearance: |
Liquid |
Handling: |
Centrifuge the vial prior to opening. |