IL-5, murine recombinant

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SKU:
4141-1000
£135.37
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Description

IL-5, murine recombinant is available at Gentaur for Next week delivery.

A cytokine which stimulates B cell growth & eosinophil activation

Biomolecule/Target: IL-5

Alternates names: Interleukin-5, IL-5, B-cell growth factor II, BCGF-II, Cytotoxic T-lymphocyte inducer, Eosinophil differentiation factor, T-cell replacing factor, TRF, Interleukin 5, IL-5, IL 5, IL-5,

Synonyms: Interleukin-5, IL-5, B-cell growth factor II, BCGF-II, Cytotoxic T-lymphocyte inducer, Eosinophil differentiation factor, T-cell replacing factor, TRF, Interleukin 5, IL-5, IL 5, IL-5,

Background Information: Mouse Interleukin-5 (mIL-5) is a glycoprotein also known as EDF and TRF. It is involved in B-cell growth and eosinophil activation. IL-5 has been shown to be expressed in Th2, mast cells and eosinophils and is regulated by GATA-3, in addition to other transcription factors. IL-5 signals its biological effect through interaction with the IL-5 receptor (IL-5R). Recombinant mIL-5 is produced in E.Coli, comprised of two 113 amino acid chains forming a disulfide-linked homodimer with a molecular weight of 26.2 kDa.

Reconstitution Instructions: It is recommended to reconstitute the lyophilized product with sterile H₂O at a concentration of 0.1 mg/ml, which can be further diluted into other aqueous solutions.

NCBI Gene Symbol: IL5

Gene ID: 16191

NCBI Accession: P04401

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Additional Information

Size:
1 mg
Adwords:
Yes
Country of Manufacturing Origin:
USA
Country of Animal Origin:
USA
Gene Source:
Mouse
Recombinant:
Yes
Source:
E. coli
Purity by SDS-PAGE:
≥97%
Assay:
SDS-PAGE
Purity:
≥97%
Assay 2:
HPLC
Endotoxin Level:
<0.1 ng/μg
Activity (Specifications/test method):
N/A
Biological activity:
Mouse IL-5 is fully biologically active as compared to standard. The ED₅₀, as calculated by the dose-dependent induction of TF-1 cell proliferation, is 1.7ng/ml.
Results:
1.7ng/ml.
Molecular Weight:
26.2 kDa
Storage Temperature:
-20°C
Shelf Life:
12 months
Concentration:
N/A
Appearance:
Lyophilized protein
Handling:
Centrifuge the vial prior to opening.
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