Description
IL-5, murine recombinant is available at Gentaur for Next week delivery.
A cytokine which stimulates B cell growth & eosinophil activation
Biomolecule/Target: IL-5
Alternates names: Interleukin-5, IL-5, B-cell growth factor II, BCGF-II, Cytotoxic T-lymphocyte inducer, Eosinophil differentiation factor, T-cell replacing factor, TRF, Interleukin 5, IL-5, IL 5, IL-5,
Synonyms: Interleukin-5, IL-5, B-cell growth factor II, BCGF-II, Cytotoxic T-lymphocyte inducer, Eosinophil differentiation factor, T-cell replacing factor, TRF, Interleukin 5, IL-5, IL 5, IL-5,
Background Information: Mouse Interleukin-5 (mIL-5) is a glycoprotein also known as EDF and TRF. It is involved in B-cell growth and eosinophil activation. IL-5 has been shown to be expressed in Th2, mast cells and eosinophils and is regulated by GATA-3, in addition to other transcription factors. IL-5 signals its biological effect through interaction with the IL-5 receptor (IL-5R). Recombinant mIL-5 is produced in E.Coli, comprised of two 113 amino acid chains forming a disulfide-linked homodimer with a molecular weight of 26.2 kDa.
Reconstitution Instructions: It is recommended to reconstitute the lyophilized product with sterile H₂O at a concentration of 0.1 mg/ml, which can be further diluted into other aqueous solutions.
NCBI Gene Symbol: IL5
Gene ID: 16191
NCBI Accession: P04401
Additional Information
Size: |
1 mg |
Adwords: |
Yes |
Country of Manufacturing Origin: |
USA |
Country of Animal Origin: |
USA |
Gene Source: |
Mouse |
Recombinant: |
Yes |
Source: |
E. coli |
Purity by SDS-PAGE: |
≥97% |
Assay: |
SDS-PAGE |
Purity: |
≥97% |
Assay 2: |
HPLC |
Endotoxin Level: |
<0.1 ng/μg |
Activity (Specifications/test method): |
N/A |
Biological activity: |
Mouse IL-5 is fully biologically active as compared to standard. The ED₅₀, as calculated by the dose-dependent induction of TF-1 cell proliferation, is 1.7ng/ml. |
Results: |
1.7ng/ml. |
Molecular Weight: |
26.2 kDa |
Storage Temperature: |
-20°C |
Shelf Life: |
12 months |
Concentration: |
N/A |
Appearance: |
Lyophilized protein |
Handling: |
Centrifuge the vial prior to opening. |