IL-22, murine recombinant

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SKU:
4602-50
$183
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Description

IL-22, murine recombinant is available at Gentaur for Next week delivery.

A potent mediator of cellular inflammatory responses

Biomolecule/Target: IL-22

Alternates names: IL-TIF, TIFa, IL-10-related T-cell-derived-inducible factor, IL-22, ILTIF, IL-D110, zcyto18, MGC79382, MGC79384, TIFIL-23

Synonyms: IL-TIF, TIFa, IL-10-related T-cell-derived-inducible factor, IL-22, ILTIF, IL-D110, zcyto18, MGC79382, MGC79384, TIFIL-23

Background Information: Murine Interleukin-22 (IL-22), also known as T cell-derived inducible factor (ILTIF), is a cytokine that is structurally related to IL-10. Studies have shown that IL-22 induces acute-phase reactants in vitro and in vivo, suggesting that the cytokine contributes to the regulation of inflammatory responses. Recombinant murine IL-22 contains 2 x 146 amino acid chains having a total molecular mass of 33.4 kDa.

Reconstitution Instructions: Reconstitute in H₂O to a concentration of 0.1 to 1.0 mg/ml. This solution can then be stored at 4°C for 1 week or -20°C for future use. For long term storage, it is recommended to add a carrier protein (e.g., 0.1% BSA). Avoid repeating freeze/thaw cycles.

NCBI Gene Symbol: IL22

Gene ID: 50929

NCBI Accession: Q9JJY9

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Additional Information

Size:
50 μg
Adwords:
Yes
Country of Manufacturing Origin:
USA
Country of Animal Origin:
USA
Gene Source:
Mouse
Recombinant:
Yes
Source:
E. coli
Purity by SDS-PAGE:
≥97%
Assay:
SDS-PAGE
Purity:
≥97%
Assay 2:
HPLC
Endotoxin Level:
<0.1 ng/μg
Activity (Specifications/test method):
N/A
Biological activity:
Recombinant murine IL-22 is fully biologically active when compared to a standard. The ED₅₀ as determined by its ability to induce IL-10 secretion in Colo205 cells is less than 0.5 ng/ml, corresponding to a specific activity of 2 x 10⁶ IU/mg.
Results:
0.5 ng/ml
Molecular Weight:
33.4 kDa
Storage Temperature:
-20°C
Shelf Life:
12 months
Concentration:
N/A
Appearance:
Lyophilized protein
Handling:
Centrifuge the vial prior to opening.
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