IL-18, human recombinant

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SKU:
4179-25
€185
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Description

IL-18, human recombinant is available at Gentaur for Next week delivery.

A proinflammatory cytokine

Biomolecule/Target: IL-18

Alternates names: Interferon-γ-inducing factor, IGIF, IL-1g, IL-18, IL1F4, MGC12320, IFN-γ-inducing factor, Interleukin-1 γ, IL-1 γ, Iboctadekin.

Synonyms: Interferon-γ-inducing factor, IGIF, IL-1g, IL-18, IL1F4, MGC12320, IFN-γ-inducing factor, Interleukin-1 γ, IL-1 γ, Iboctadekin.

Background Information: Interleukin-18 (IL-18), an 18 kDa cytokine, is a single, non-glycosylated polypeptide chain containing 157 amino acids. IL-18 was previously known as interferon-g inducing factor (IGIF). This pleiotropic cytokine is produced by monocyte/macrophage cells. Like IL-12, IL-18 plays an important role in cell-mediated immune responses.

Reconstitution Instructions: Reconstitute in ice-cold H₂O to a concentration of 0.5-1 µg/µl.

NCBI Gene Symbol: IL18

Gene ID: 3606

NCBI Accession: Q14116

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Additional Information

Size:
25 μg
Adwords:
Yes
Country of Manufacturing Origin:
USA
Country of Animal Origin:
USA
Gene Source:
Human
Recombinant:
Yes
Source:
E. coli
Purity by SDS-PAGE:
≥98%
Assay:
SDS-PAGE
Purity:
≥98%
Assay 2:
HPLC
Endotoxin Level:
<0.1 ng/μg
Activity (Specifications/test method):
N/A
Biological activity:
The ED₅₀ as determined by dose-dependent stimulation of the IFNg by human PBMC co-stimulated with rh-IL-12 was found to be 5 ng/ml.
Results:
5 ng/ ml
Molecular Weight:
18.3 kDa
Storage Temperature:
-20°C
Shelf Life:
12 months
Concentration:
N/A
Appearance:
Lyophilized protein
Handling:
Centrifuge the vial prior to opening.
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