IL-17B, Human Recombinant

IL-17B, Human Recombinant is available at Gentaur for Next week delivery.

A cytokine expressed by T-cells, which stimulates the release of TNF-α and IL-1β from cells of the monocyte lineage

Biomolecule/Target: IL-17B

Alternates names: IL20, NIRF

Synonyms: IL20, NIRF

Background Information: IL-17B is a disulfide-linked homodimer of two 161 amino acid polypeptide chains. It belongs to the IL-17 family of structurally-related cytokines that share a highly conserved C-terminal region but differ from one another in their N-terminal regions and in their distinct biological roles. The six known members of this family, IL-17A through IL-17F, are secreted as homodimers. IL-17B is expressed by T-cells and has been shown to stimulate release of TNF-α and IL-1β from cells of the monocyte lineage. Recombinant human IL-17B is a 36.6 kDa nondisulfide-linked homodimer of two 161 amino acid polypeptide chains.

Reconstitution Instructions: Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1-1.0 mg/ml. Do not vortex. This solution can be stored at 2-8°C for up to 1 week. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein (example 0.1% BSA) and store in working aliquots at -20°C to -80°C.

NCBI Gene Symbol: IL17B

Gene ID: 27190

NCBI Accession: Q9UHF5