IL-10, murine recombinant

(No reviews yet) Write a Review
SKU:
4156-50
$719.07
Frequently bought together:

Description

IL-10, murine recombinant is available at Gentaur for Next week delivery.

An anti-inflammatory cytokine

Biomolecule/Target: IL-10

Alternates names: B-TCGF, CSIF, TGIF, IL-10, IL10A, MGC126450, MGC126451, Cytokine synthesis inhibitory factor.

Synonyms: B-TCGF, CSIF, TGIF, IL-10, IL10A, MGC126450, MGC126451, Cytokine synthesis inhibitory factor.

Background Information: IL-10 is an immunosuppressive cytokine produced by a variety of mammalian cell types including macrophages, monocytes, T cells, B cells and keratinocytes. IL-10 inhibits the expression of proinflammatory cytokines such as IL-1 and TNF-Ą. Like IL-4, IL-10 enhances humoral immune responses and attenuates cell-mediated immune reactions. Human IL-10 active on murine cells, but murine IL-10 is inactive on human cells. Recombinant murine IL-10 is an 18.7 kDa protein of 161 amino acid residues.

Reconstitution Instructions: Reconstitute in 3 mM Tris, pH 8.0 to a concentration of 0.1-1.0 µg/µl. The solution can then be diluted into other aqueous buffers and stored at 4°C for 1 week or –20°C for future use.

NCBI Gene Symbol: IL10

Gene ID: 16153

NCBI Accession: P18893

View AllClose

Additional Information

Size:
50 μg
Adwords:
Yes-SG
Country of Manufacturing Origin:
USA
Country of Animal Origin:
USA
Gene Source:
Mouse
Recombinant:
Yes
Source:
E. coli
Purity by SDS-PAGE:
≥98%
Assay:
SDS-PAGE
Purity:
≥98%
Assay 2:
HPLC
Endotoxin Level:
<0.1 ng/μg
Activity (Specifications/test method):
N/A
Biological activity:
The ED₅₀ determined by the dose-dependent co-stimulation (with murine IL-4) of MC/9 cells is <2 ng/ml, corresponding to a specific activity of > 5 x 10⁵ units/mg.
Results:
<2 ng/ml
Molecular Weight:
18.7 kDa
Storage Temperature:
-20°C
Shelf Life:
12 months
Concentration:
N/A
Appearance:
Lyophilized protein
Handling:
Centrifuge the vial prior to opening.
View AllClose

0 Reviews

View AllClose