IL-10, human recombinant

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SKU:
4155-50
$183
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Description

IL-10, human recombinant is available at Gentaur for Next week delivery.

An anti-inflammatory cytokine

Biomolecule/Target: IL-10

Alternates names: B-TCGF, CSIF, TGIF, IL-10, IL10A, MGC126450, MGC126451, Cytokine synthesis inhibitory factor.

Synonyms: B-TCGF, CSIF, TGIF, IL-10, IL10A, MGC126450, MGC126451, Cytokine synthesis inhibitory factor.

Background Information: IL-10 (Interleukin-10), originally known as Cytokine Synthesis Inhibitory Factor (CSIF), is an 18.6 kDa protein containing 161 amino acid residues. It shares over 80% sequence homology with the Epstein-Barr Virus protein BCRFI. The reported biological activities of IL-10 include inhibition of macrophage-mediated cytokine synthesis, suppression of the delayed-type hypersensitivity response, and stimulation of the Th2 cell response which results in elevated antibody production.

Reconstitution Instructions: Reconstitute in H₂O a concentration of 0.1-1.0 µg/µl. The solution can then be diluted into other aqueous buffers and stored at 4°C for 1 week or –20°C for future use.

NCBI Gene Symbol: IL10

Gene ID: 3586

NCBI Accession: P22301

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Additional Information

Size:
50 μg
Adwords:
Yes-SG
Country of Manufacturing Origin:
USA
Country of Animal Origin:
USA
Gene Source:
Human
Recombinant:
Yes
Source:
E. coli
Purity by SDS-PAGE:
≥98%
Assay:
SDS-PAGE
Purity:
≥98%
Assay 2:
HPLC
Endotoxin Level:
<0.1 ng/μg
Activity (Specifications/test method):
N/A
Biological activity:
The ED₅₀ determined by the dose-dependent co-stimulation (with murine IL-4) of MC/9 cells is < 2 ng/ml, corresponding to a specific activity of > 5 x 10⁵ units/mg.
Results:
< 2 ng/ml
Molecular Weight:
19.6 kDa
Storage Temperature:
-20°C
Shelf Life:
12 months
Concentration:
N/A
Appearance:
Lyophilized protein
Handling:
Centrifuge the vial prior to opening.
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