Description
IGF-BP1, human recombinant is available at Gentaur for Next week delivery.
A protein which binds and prolongs the half-life of the IGFs
Biomolecule/Target:
Alternates names: IBP-1, IGF-Binding Protein 1, AFBP, PP12, IGF-BP25, hIGFBP-1, IGFBP-1.
Synonyms: IBP-1, IGF-Binding Protein 1, AFBP, PP12, IGF-BP25, hIGFBP-1, IGFBP-1.
Background Information: Human IGF-BP1 is a 25.4 kDa cysteine-rich secreted protein expressed in liver, decidual, and kidneys and is the most abundant IGF-BP in amniotic fluid. Levels of IGF-BP1 in serum are lowest after food. IGF-BP1 binds both IGF-I and IGF-II with equal affinity. Phosphorylated IGF-BP1 hinders IGF actions, whereas nonphosphorylated IGF-BP1 is stimulatory. Recombinant human IGF-BP1 is a single, glycosylated protein consisting of 218 amino acid residues.
Reconstitution Instructions: Reconstitute in H₂O to a concentration of 0.1-1.0 mg/ml. The solution can then be diluted into other aqueous buffers and store at 4°C for 1 week or –20°C for future use.
NCBI Gene Symbol: IBP1
Gene ID: 3484
NCBI Accession: P08833
Additional Information
Size: |
25 μg |
Country of Manufacturing Origin: |
USA |
Country of Animal Origin: |
USA |
Gene Source: |
Human |
Recombinant: |
Yes |
Source: |
Nso cells |
Purity by SDS-PAGE: |
≥98% |
Assay: |
SDS-PAGE |
Purity: |
≥98% |
Assay 2: |
HPLC |
Endotoxin Level: |
<0.1 ng/μg |
Activity (Specifications/test method): |
N/A |
Biological activity: |
The ED₅₀ as determined by its ability to inhibit IGF-I induced proliferation of NUC-1 cells is ~100 ng/ml. |
Results: |
~100 ng/ml |
Molecular Weight: |
28.8 kDa |
Storage Temperature: |
-20°C |
Shelf Life: |
12 months |
Concentration: |
N/A |
Appearance: |
Lyophilized protein |
Handling: |
Centrifuge the vial prior to opening. |