ICAM-3, Human Recombinant

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SKU:
P1564-20
€185
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Description

ICAM-3, Human Recombinant is available at Gentaur for Next week delivery.

Contributes to apoptotic neutrophil phagocytosis by macrophages

Biomolecule/Target:

Alternates names: ICAM3, Intercellular adhesion molecule 3, ICAM-3, CD50, CDW50, ICAM-R, intercellular adhesion molecule 3 isoform 1

Synonyms: ICAM3, Intercellular adhesion molecule 3, ICAM-3, CD50, CDW50, ICAM-R, intercellular adhesion molecule 3 isoform 1

Background Information: ICAM-3/CD50, also known as CD50 (Cluster of Differentiation 50), is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulinlike C2-type domains, and bind to the leukocyte adhesion LFA-1 protein. This protein is constitutively and abundantly expressed by all leukocytes and maybe the most important ligand for LFA-1 in the initiation of the immune response. It functions not only as an adhesion molecule, but also as a potent signaling molecule. Recombinant human ICAM-3/CD50, fused hIgG-His-tag at C-terminus, was expressed in the insect cell and purified by using conventional chromatography techniques.

Reconstitution Instructions:

NCBI Gene Symbol: ICAM3

Gene ID: 3385

NCBI Accession: P32942

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Additional Information

Size:
50 µg
Adwords:
FAUX
Country of Manufacturing Origin:
USA
Country of Animal Origin:
USA
Gene Source:
Human
Recombinant:
VRAI
Source:
Baculovirus
Purity by SDS-PAGE:
>95%
Assay:
SDS - PAGE
Endotoxin Level:
< 1 EU per 1ug of protein (determined by LAL method)
Biological activity:
Measured by the ability of the immobilized protein to support the adhesion of HL-60 human promyelocytic cells. When cells are added to Human ICAM-3/CD50 coated plates, the ED50 range ≤4ug/ml.
Molecular Weight:
76.7 kDa (hIgG-His-tag at C-terminus)
Storage Temperature:
-20°C
Shelf Life:
12 months
Appearance:
Liquid
Handling:
Centrifuge the vial prior to opening.
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