Human Thyroglobulin

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SKU:
P1025-20
€185
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Description

Human Thyroglobulin is available at Gentaur for Next week delivery.

Precursor of the iodinated thyroid hormones thyroxine (T4) and triiodothyronine (T3).

Biomolecule/Target: TG

Alternates names: Thyroglobulin, TGN, AITD3, TG

Synonyms: Thyroglobulin, TGN, AITD3, TG

Background Information: Thyroglobulin (TG) represents one of the main autoantigenic targets in autoimmune thyroid disease of humans. TG is a large globular dimeric glycoprotein with a total molecular weight of 660 kDa, which occupies a key precursor role in the biosynthesis of the thyroid hormones. Approximately 75% of the total protein content of the thyroid follicle consists of TG. The thyroid gland uses the Thyroglobulin in order to produce the thyroid hormones thyroxine (T4) and triiodothyronine (T3). Thyroglobulin is produced by the thyroid epithelial cells (thyrocytes) which form spherical follicles. Thyroglobulin is subsequently secreted and stored in the follicular lumen.

Reconstitution Instructions: N/A

NCBI Gene Symbol: TG

Gene ID: 7038

NCBI Accession: P01266

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Additional Information

Size:
20 μg
Country of Manufacturing Origin:
USA
Country of Animal Origin:
USA
Gene Source:
Human
Recombinant:
No
Source:
N/A
Purity by SDS-PAGE:
> 95%
Assay:
SDS-PAGE
Purity:
N/A
Assay 2:
N/A
Endotoxin Level:
N/A
Activity (Specifications/test method):
N/A
Biological activity:
N/A
Results:
N/A
Molecular Weight:
331 kDa
Storage Temperature:
-20°C
Shelf Life:
12 months
Concentration:
N/A
Appearance:
Liquid
Handling:
Centrifuge the vial prior to opening.
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