Human Recombinant UCHL3

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SKU:
6358-100
€185
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Description

Human Recombinant UCHL3 is available at Gentaur for Next week delivery.

A deubiquitinating enzyme

Biomolecule/Target:

Alternates names: Ubiquitin carboxyl-terminal hydrolase isozyme L3, UCH-L3, Ubiquitin thioesterase L3

Synonyms: Human Recombinant UCHL3

Background Information: Ubiquitin C-terminal hydrolases (UCHs) are a family of cysteine hydrolases that catalyze the hydrolysis of amides, esters and thioesters of the C-terminus of ubiquitin. UCH-L3 is a member of the lower molecular weight group of UCHs involved in the hydrolysis of small C-terminal derivatives of ubiquitin that form non-specifically during the process of protein ubiquitinylation. UCHL3 play a role in the regulation of neuronal development and spermatogenesis and have been implicated in neurodegenerative diseases.

Reconstitution Instructions: N/A

NCBI Gene Symbol: UCHL3

Gene ID: 7347

NCBI Accession: P15374

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Additional Information

Size:
100 μg
Country of Manufacturing Origin:
USA
Country of Animal Origin:
USA
Gene Source:
Human
Recombinant:
Yes
Source:
E. Coli
Purity by SDS-PAGE:
≥95%
Assay:
SDS-PAGE
Purity:
N/A
Assay 2:
N/A
Endotoxin Level:
N/A
Activity (Specifications/test method):
N/A
Biological activity:
Specific activity: >3000 pmole/min/µg. Measured by the hydrolysis of Ubiquitin-AMC at pH 8.0, at 37°C.
Results:
N/A
Molecular Weight:
28.3 kDa (250 aa, 1-230 aa + NT His Tag)
Storage Temperature:
-20°C
Shelf Life:
12 months
Concentration:
1 mg/ml
Appearance:
Liquid
Handling:
Centrifuge the vial prior to opening.
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