Human recombinant Ubiquitin Activating Enzyme E1

(No reviews yet) Write a Review
SKU:
6429-50
€185
Frequently bought together:

Description

Human recombinant Ubiquitin Activating Enzyme E1 is available at Gentaur for Next week delivery.

First enzyme involved in ubiquitin conjugation pathway, conjugating ubiquitin to the substrate.

Biomolecule/Target:

Alternates names: UBE1, UBA1, POC20, A1S9T, A1ST, AMCX1, GXP1, SMAX2

Synonyms: Human recombinant Ubiquitin Activating Enzyme E1

Background Information: UBE1, the ubiquitin activating enzyme, is the first enzyme utilized in the pathway to conjugate ubiquitin onto target substrates through an ubiquitin-protein isopeptide bond. The C-terminal glycine of an ubiquitin (G76) is initially adenylated in an ATP dependent manner activating it so it can be transferred to the active site cysteine of UBE1 forming an ubiquitin-UBE1 thiolester. With the help of the other enzymes in the ubiquitin conjugation pathway (E2/E3 enzymes) the ubiquitin is transferred to a specific lysine on a target substrate.

Reconstitution Instructions: N/A

NCBI Gene Symbol: UBA1

Gene ID: 7317

NCBI Accession: P22314

View AllClose

Additional Information

Size:
50 μg
Country of Manufacturing Origin:
USA
Country of Animal Origin:
USA
Gene Source:
Human
Recombinant:
Yes
Source:
N/A
Purity by SDS-PAGE:
≥95%
Assay:
SDS-PAGE
Purity:
N/A
Assay 2:
N/A
Endotoxin Level:
N/A
Activity (Specifications/test method):
N/A
Biological activity:
Typical enzyme concentration of 5 nM – 100 nM is used for in vitro conjugation, depending on conditions.
Results:
N/A
Molecular Weight:
118 kDa
Storage Temperature:
-80°C
Shelf Life:
12 months
Concentration:
N/A
Appearance:
Liquid
Handling:
Centrifuge the vial prior to opening.
View AllClose

0 Reviews

View AllClose