Description
Human recombinant UBE2D3 is available at Gentaur for Next week delivery.
Ubiquitin conjugating enzyme involved in conjugation of ubiquitin to target substrates.
Biomolecule/Target:
Alternates names: Ubiquitin-conjugating enzyme E2 D3, Ubiquitin-protein ligase D3, Ubiquitin carrier protein D3, Ubiquitin-conjugating enzyme E2-17 kDa 3, UBC4/5, UBCH5C, MGC5416, MGC43926, UBE2D3.
Synonyms: Human recombinant UBE2D3
Background Information: UBE2D3 (UbcH5b) is an E2 (ubiquitin conjugating enzyme) that is involved in the conjugation of ubiquitin to target substrates along with E1 and E3 enzymes. The UbcH5 family (including UbcH5a and UbcH5c, having 88% and 89% sequence identity with UbcH5b respectively) are the human homologues of the Saccharomyces cerevisiae UBC4/5 family (~79% sequence identity). Members of the UbcH5 family have been implicated in a number of inflammatory and cancer pathways including the ubiquitylation of p53 and IκBα with the help of different E3 ligases (Hdm2 and SCF complexes respectively).
Reconstitution Instructions: N/A
NCBI Gene Symbol: UBE2D3
Gene ID: 7323
NCBI Accession: P61077
Additional Information
Size: |
3 nmol |
Country of Manufacturing Origin: |
USA |
Country of Animal Origin: |
USA |
Gene Source: |
Human |
Recombinant: |
Yes |
Source: |
N/A |
Purity by SDS-PAGE: |
≥95% |
Assay: |
RP-HPLC |
Purity: |
N/A |
Assay 2: |
N/A |
Endotoxin Level: |
N/A |
Activity (Specifications/test method): |
N/A |
Biological activity: |
Typical enzyme concentration of 100 nM - 1 mM is used for in vitro conjugation, depending on conditions. |
Results: |
N/A |
Molecular Weight: |
28.707 kDa with a His6SUMO Tag |
Storage Temperature: |
-80°C |
Shelf Life: |
12 months |
Concentration: |
N/A |
Appearance: |
Liquid |
Handling: |
Centrifuge the vial prior to opening. |