Human Recombinant PPM1G

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SKU:
6369-50
$183
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Description

Human Recombinant PPM1G is available at Gentaur for Next week delivery.

Negative regulator of cell stress response pathways

Biomolecule/Target:

Alternates names: Protein phosphatase 1G, PP2CG, PPP2CG, MGC1675, MGC2870, PP2CGAMMA.

Synonyms: Human Recombinant PPM1G

Background Information: PPM1G is part of the PP2C family of Ser/Thr protein phosphatases which are known to be negative regulators of cell stress response pathways. PPM1G is accountable for the dephosphorylation of Pre-mRNA splicing factors, an important factor for the formation of functional spliceosome. PPM1G regulates cell cycle progression. PPM1G mediates histone dephosphorylation/exchange in response to DNA damage or checkpoint recovery in higher eukaryotes. The degradation of p21/WAF1 induced by PPM1G is mediated in a proteasome-dependent manner. Protein phosphatase 1G regulates assembly and function of the beta-catenin degradation complex.

Reconstitution Instructions: N/A

NCBI Gene Symbol: PPM1G

Gene ID: 5496

NCBI Accession: O15355

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Additional Information

Size:
50 μg
Country of Manufacturing Origin:
USA
Country of Animal Origin:
USA
Gene Source:
Human
Recombinant:
Yes
Source:
E. Coli
Purity by SDS-PAGE:
≥85%
Assay:
SDS-PAGE
Purity:
N/A
Assay 2:
N/A
Endotoxin Level:
N/A
Activity (Specifications/test method):
N/A
Biological activity:
Specific activity: >5,000 units/mg.
Results:
>5,000 units/mg
Molecular Weight:
61.4 kDa (566 aa, 1-546 aa + NT His-Tag)
Storage Temperature:
-20°C
Shelf Life:
12 months
Concentration:
1 mg/ml
Appearance:
Liquid
Handling:
Centrifuge the vial prior to opening.
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