Human Recombinant PKLR

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SKU:
6373-50
£135.37
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Description

Human Recombinant PKLR is available at Gentaur for Next week delivery.

Catalyzes the rate-limiting step of glycolysis

Biomolecule/Target:

Alternates names: Pyruvate kinase isozyme R/L, PK1, PKL, PKR, PKRL, RPK.

Synonyms: Human Recombinant PKLR

Background Information: PKLR is a pyruvate kinase which catalyzes the trans phosphorylation of Phosphoenolpyruvate into pyruvate and ATP. That is the rate-limiting step of glycolysis. PKLR gene encodes the L- and R-type isoenzymes through alternate splicing events controlled by different promoters. The L-type isoform can also appear as a tetramer and is upregulated by glucose with implications in maturity-onset diabetes of the young.

Reconstitution Instructions: N/A

NCBI Gene Symbol: PKLR

Gene ID: 5313

NCBI Accession: P30613

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Additional Information

Size:
50 μg
Country of Manufacturing Origin:
USA
Country of Animal Origin:
USA
Gene Source:
Human
Recombinant:
Yes
Source:
E. Coli
Purity by SDS-PAGE:
≥90%
Assay:
SDS-PAGE
Purity:
N/A
Assay 2:
N/A
Endotoxin Level:
N/A
Activity (Specifications/test method):
N/A
Biological activity:
Specific activity: >0.1 unit/mg.
Results:
>0.1 unit/mg
Molecular Weight:
59.2 kDa (549 aa, 47-574 aa + NT His-Tag)
Storage Temperature:
-20°C
Shelf Life:
12 months
Concentration:
1 mg/ml
Appearance:
Liquid
Handling:
Centrifuge the vial prior to opening.
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