Human Recombinant PAI-1

Human Recombinant PAI-1 is available at Gentaur for Next week delivery.

Activator of plasminogen and fibrinolysis

Biomolecule/Target:

Alternates names: Plasminogen activator inhibitor-1, SERPINE1, PAI, PAI1, PLANH1.

Synonyms: Human Recombinant PAI-1

Background Information: Plasminogen activator inhibitor-1 is the principal inhibitor of tissue plasminogen activator (tPA) and Urokinase (uPA), the activators of plasminogen and hence fibrinolysis (the physiological breakdown of blood clots). It is a serine protease inhibitor (serpin) protein (SERPINE1). The other PAI, plasminogen activator inhibitor-2 (PAI-2) is secreted by the placenta and only present in significant amounts during pregnancy. In addition, protease nexin acts as an inhibitor of tPA and urokinase. SERPINE1, however, is the main inhibitor of the plasminogen activators.

Reconstitution Instructions: N/A

NCBI Gene Symbol: SERPINE1

Gene ID: 5054

NCBI Accession: P05121