Human Recombinant LDHA

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SKU:
6374-100
$183
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Description

Human Recombinant LDHA is available at Gentaur for Next week delivery.

Catalyzes the final step of anaerobic glycolysis

Biomolecule/Target:

Alternates names: L-lactate dehydrogenase A chain, GSD11, LDH1, LDHM, PIG19.

Synonyms: Human Recombinant LDHA

Background Information: LDHA catalyzes the conversion of L-lactate and NAD to pyruvate and NADH in the final step of anaerobic glycolysis. LDHA is localized primarily in muscle tissue and is part of the lactate dehydrogenase family. Mutations in LDHA have been linked to exertional myoglobinuria. LDH1 is decreased in essential thrombocythemia. LDHA is induced through a non-genomic pathway of estrogen action. Reduction in LDH-A activity results in stimulation of mitochondrial respiration and decrease of mitochondrial membrane potential.

Reconstitution Instructions: N/A

NCBI Gene Symbol: LDHA

Gene ID: 3939

NCBI Accession: P00338

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Additional Information

Size:
100 μg
Country of Manufacturing Origin:
USA
Country of Animal Origin:
USA
Gene Source:
Human
Recombinant:
Yes
Source:
E. Coli
Purity by SDS-PAGE:
≥95%
Assay:
SDS-PAGE
Purity:
N/A
Assay 2:
N/A
Endotoxin Level:
N/A
Activity (Specifications/test method):
N/A
Biological activity:
Specific activity is >20 units/mg.
Results:
>20 units/mg
Molecular Weight:
38.8 kDa (352 aa, 1-332 aa + His-Tag)
Storage Temperature:
-20°C
Shelf Life:
12 months
Concentration:
0.5 mg/ml
Appearance:
Liquid
Handling:
Centrifuge the vial prior to opening.
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