Description
Human Recombinant Fumarase is available at Gentaur for Next week delivery.
Involved in the TCA or Krebs cycle
Biomolecule/Target:
Alternates names: Fumarate hydratase, FH, HLRCC, LRCC, MCL, MCUL1.
Synonyms: Human Recombinant Fumarase
Background Information: Fumarase (Fumarate hydratase) is an enzyme that catalyzes the reversible hydration/dehydration of fumarate to S-malate and is involved in the tricarboxylic acid (TCA), or Krebs cycle. This enzyme exists in both a cytosolic form and an N-terminal extended mitochondrial form. The N-terminal extended form is targeted to the mitochondrion, where the removal of the extension is the same form as in the cytoplasm. Fumarase deficiency can lead to progressive encephalopathy, cerebral atrophy and developmental delay and this enzyme also is thought to act as a tumor suppressor.
Reconstitution Instructions: N/A
NCBI Gene Symbol: FH
Gene ID: 2271
NCBI Accession: P07954
Additional Information
Size: |
100 μg |
Country of Manufacturing Origin: |
USA |
Country of Animal Origin: |
USA |
Gene Source: |
Human |
Recombinant: |
Yes |
Source: |
E. Coli |
Purity by SDS-PAGE: |
≥95% |
Assay: |
SDS-PAGE |
Purity: |
N/A |
Assay 2: |
N/A |
Endotoxin Level: |
< 1.0 EU per 1 μg of protein (determined by LAL method) |
Activity (Specifications/test method): |
N/A |
Biological activity: |
Specific activity is > 1.0 unit/mg |
Results: |
>1.0 unit/mg |
Molecular Weight: |
50.2 kDa (467 aa, 44-510 aa) |
Storage Temperature: |
-20°C |
Shelf Life: |
12 months |
Concentration: |
1 mg/ml |
Appearance: |
Liquid |
Handling: |
Centrifuge the vial prior to opening. |