Human Recombinant FKBP3

Human Recombinant FKBP3 is available at Gentaur for Next week delivery.

An immunophilin family protein functioning as a protein folding chaperone

Biomolecule/Target:

Alternates names: FK506 binding protein 3, FKBP25, PPIase FKBP3, Rotamase

Synonyms: Human Recombinant FKBP3

Background Information: FKBP3 is part of a family of immunosuppressant receptors which inhibit T-cell proliferation by arresting two distinct cytoplasmic signal transmission pathways. FKBP3 accelerates the folding of proteins. FKBP3 is part of the immunophilin protein family, which participates in immunoregulation and fundamental cellular processes concerning protein folding and trafficking. FKBP3 is a cis-trans prolyl isomerase enzyme that binds the immunosuppressants FK506 and rapamycin, as well as histone deacetylases, the transcription factor YY1, casein kinase II, and nucleolin. It has a greater affinity for rapamycin than for FK506 and therefore is a significant protein for immunosuppression by rapamycin.

Reconstitution Instructions: N/A

NCBI Gene Symbol: FKBP3

Gene ID: 2287

NCBI Accession: Q00688