Description
Human Recombinant DUSP3 is available at Gentaur for Next week delivery.
Negatively regulates MAPK superfamily members
Biomolecule/Target:
Alternates names: Dual specificity protein phosphatase 3, VHR.
Synonyms: Human Recombinant DUSP3
Background Information: DUSP3 belongs to the dual specificity protein phosphatase subfamily which inactivates their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. DUSP3 negatively regulate members of the mitogen-activated protein kinase superfamily that are related to cellular proliferation and differentiation. DUSP3 is expressed in both breast and ovarian tissues and displays activity both for tyrosine-protein phosphate and serine-protein phosphate, but exhibits a strong preference toward phosphotyrosines, specifically dephosphorylates and inactivates ERK1 and ERK2.
Reconstitution Instructions: N/A
NCBI Gene Symbol: DUSP3
Gene ID: 1845
NCBI Accession: P51452
Additional Information
Size: |
100 μg |
Country of Manufacturing Origin: |
USA |
Country of Animal Origin: |
USA |
Gene Source: |
Human |
Recombinant: |
Yes |
Source: |
E. Coli |
Purity by SDS-PAGE: |
≥95% |
Assay: |
SDS-PAGE |
Purity: |
N/A |
Assay 2: |
N/A |
Endotoxin Level: |
N/A |
Activity (Specifications/test method): |
N/A |
Biological activity: |
Specific activity: >1750 units/mg. |
Results: |
>1750 units/mg |
Molecular Weight: |
22.6 kDa (205 aa, 1-185 aa + NT His-Tag) |
Storage Temperature: |
-20°C |
Shelf Life: |
12 months |
Concentration: |
1 mg/ml |
Appearance: |
Liquid |
Handling: |
Centrifuge the vial prior to opening. |
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