Human Recombinant DUSP3

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SKU:
6371-100
£135.37
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Description

Human Recombinant DUSP3 is available at Gentaur for Next week delivery.

Negatively regulates MAPK superfamily members

Biomolecule/Target:

Alternates names: Dual specificity protein phosphatase 3, VHR.

Synonyms: Human Recombinant DUSP3

Background Information: DUSP3 belongs to the dual specificity protein phosphatase subfamily which inactivates their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. DUSP3 negatively regulate members of the mitogen-activated protein kinase superfamily that are related to cellular proliferation and differentiation. DUSP3 is expressed in both breast and ovarian tissues and displays activity both for tyrosine-protein phosphate and serine-protein phosphate, but exhibits a strong preference toward phosphotyrosines, specifically dephosphorylates and inactivates ERK1 and ERK2.

Reconstitution Instructions: N/A

NCBI Gene Symbol: DUSP3

Gene ID: 1845

NCBI Accession: P51452

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Additional Information

Size:
100 μg
Country of Manufacturing Origin:
USA
Country of Animal Origin:
USA
Gene Source:
Human
Recombinant:
Yes
Source:
E. Coli
Purity by SDS-PAGE:
≥95%
Assay:
SDS-PAGE
Purity:
N/A
Assay 2:
N/A
Endotoxin Level:
N/A
Activity (Specifications/test method):
N/A
Biological activity:
Specific activity: >1750 units/mg.
Results:
>1750 units/mg
Molecular Weight:
22.6 kDa (205 aa, 1-185 aa + NT His-Tag)
Storage Temperature:
-20°C
Shelf Life:
12 months
Concentration:
1 mg/ml
Appearance:
Liquid
Handling:
Centrifuge the vial prior to opening.
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