Human Recombinant Cyclophilin A

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SKU:
6311-100
$719.07
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Description

Human Recombinant Cyclophilin A is available at Gentaur for Next week delivery.

An immunophilin family protein catalyzing the isomerization of peptide bonds

Biomolecule/Target:

Alternates names: Peptidylprolyl isomerase A, PPIA, CYPA, CYPH

Synonyms: Human Recombinant Cyclophilin A

Background Information: Cyclophilin A is a multifunctional protein that is upregulated in a variety of inflammatory conditions, such as rheumatoid arthritis, autoimmune disease, and cancer. It has been classified as an immunophilin and has a variety of intracellular functions, including intracellular signaling, protein trafficking, and the regulation of other proteins activity. Besides its intracellular functions, Cyclophilin A is a secreted molecule that has a physiological and pathological role in cardiovascular diseases, making it a potential biomarker and mediator in cardiovascular diseases, such as vascular stenosis, atherosclerosis, and abdominal aortic aneurysms.

Reconstitution Instructions: N/A

NCBI Gene Symbol: PPIA

Gene ID: 5478

NCBI Accession: P62937

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Additional Information

Size:
100 μg
Country of Manufacturing Origin:
USA
Country of Animal Origin:
USA
Gene Source:
Human
Recombinant:
Yes
Source:
E. coli
Purity by SDS-PAGE:
≥95%
Assay:
SDS-PAGE
Purity:
N/A
Assay 2:
N/A
Endotoxin Level:
< 1.0 EU per 1 μg of protein (determined by LAL method)
Activity (Specifications/test method):
N/A
Biological activity:
Specific activity is > 270 nmoles/min/mg
Molecular Weight:
20 kDa
Storage Temperature:
-20°C
Shelf Life:
12 months
Concentration:
1 mg/ml
Appearance:
Liquid
Handling:
Centrifuge the vial prior to opening.
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