Description
Human GLS1, Recombinant is available at Gentaur for Next week delivery.
A mitochondrial enzyme that hydrolyzes glutamine producing glutamate and ammonia
Biomolecule/Target:
Alternates names: Glutaminase, cKGA, catalytic domain of KGA, Glutaminase kidney isoform, mitochondrial, KGA, GLS1, GAC, GAM, KGA
Synonyms: Glutaminase, cKGA, catalytic domain of KGA, Glutaminase kidney isoform, mitochondrial, KGA, GLS1, GAC, GAM, KGA
Background Information: Glutaminase (EC 3.5.1.2) is a mitochondrial enzyme that hydrolyzes glutamine producing glutamate and ammonia. GLS is one of the two key enzymes including glutamine synthetase that are responsible for glutamine homeostasis. Since glutamine is a major metabolic substrate involved in gluconeogenesis, its homeostasis is tightly controlled. Glutaminase has tissue-specific roles in multiple organs, with the isoform GLS1 being expressed in kidneys and brain, and GLS2 being expressed in the liver. It is involved in maintenance of acid-base homeostasis by producing ammonia during renal acidosis in kidneys and regulation of glutamate, which acts as a neurotransmitter in the brain. BioVision’s recombinant GLS1 is catalytic domain of the original GLS1, which shows greater activity and excellent stability.
Reconstitution Instructions:
NCBI Gene Symbol:
NCBI Accession: O94925
Additional Information
Size: |
50 µg |
Adwords: |
FAUX |
Country of Manufacturing Origin: |
USA |
Country of Animal Origin: |
N/A |
Gene Source: |
E Coli |
Recombinant: |
VRAI |
Purity by SDS-PAGE: |
≥ 95% by SDS-PAGE |
Biological activity: |
Biological activity was performed using BioVision’s Glutaminase Activity Assay Kit (Colorimetric) (Cat# K2067-100). |
Molecular Weight: |
36.7 kDa |
Storage Temperature: |
-70°C |
Shelf Life: |
12 months |
Concentration: |
Lot specific |
Appearance: |
Colorless liquid |
Handling: |
Centrifuge the vial prior to opening. |