Human GLS1, Recombinant

(No reviews yet) Write a Review
SKU:
P1656-50
€185
Frequently bought together:

Description

Human GLS1, Recombinant is available at Gentaur for Next week delivery.

A mitochondrial enzyme that hydrolyzes glutamine producing glutamate and ammonia

Biomolecule/Target:

Alternates names: Glutaminase, cKGA, catalytic domain of KGA, Glutaminase kidney isoform, mitochondrial, KGA, GLS1, GAC, GAM, KGA

Synonyms: Glutaminase, cKGA, catalytic domain of KGA, Glutaminase kidney isoform, mitochondrial, KGA, GLS1, GAC, GAM, KGA

Background Information: Glutaminase (EC 3.5.1.2) is a mitochondrial enzyme that hydrolyzes glutamine producing glutamate and ammonia. GLS is one of the two key enzymes including glutamine synthetase that are responsible for glutamine homeostasis. Since glutamine is a major metabolic substrate involved in gluconeogenesis, its homeostasis is tightly controlled. Glutaminase has tissue-specific roles in multiple organs, with the isoform GLS1 being expressed in kidneys and brain, and GLS2 being expressed in the liver. It is involved in maintenance of acid-base homeostasis by producing ammonia during renal acidosis in kidneys and regulation of glutamate, which acts as a neurotransmitter in the brain. BioVision’s recombinant GLS1 is catalytic domain of the original GLS1, which shows greater activity and excellent stability.

Reconstitution Instructions:

NCBI Gene Symbol:

Gene ID:

NCBI Accession: O94925

View AllClose

Additional Information

Size:
50 µg
Adwords:
FAUX
Country of Manufacturing Origin:
USA
Country of Animal Origin:
N/A
Gene Source:
E Coli
Recombinant:
VRAI
Purity by SDS-PAGE:
≥ 95% by SDS-PAGE
Biological activity:
Biological activity was performed using BioVision’s Glutaminase Activity Assay Kit (Colorimetric) (Cat# K2067-100).
Molecular Weight:
36.7 kDa
Storage Temperature:
-70°C
Shelf Life:
12 months
Concentration:
Lot specific
Appearance:
Colorless liquid
Handling:
Centrifuge the vial prior to opening.
View AllClose

0 Reviews

View AllClose