BioVision Proteins
Human CellExp™ Siglec-2 / CD22, Mouse Recombinant
- SKU:
- P1330-50
Description
Human CellExp™ Siglec-2 / CD22, Mouse Recombinant is available at Gentaur for Next week delivery.
Mediates B-cell B-cell interactions and involved in the localization of B-cells in lymphoid tissues
Biomolecule/Target: CD22
Alternates names: CD22, SIGLEC2, BL-CAM, Leu-14
Synonyms: CD22, SIGLEC2, BL-CAM, Leu-14
Background Information: B-cell receptor CD22 is also known as Sialic acid-binding Ig-like lectin 2 (Siglec-2), B-lymphocyte cell adhesion molecule (BL-CAM), T-cell surface antigen Leu-14, which belongs to the immunoglobulin superfamily and SIGLEC (sialic acid binding Ig-like lectin) family. CD22 mediates B-cell B-cell interactions, and may be involved in the localization of B-cells in lymphoid tissues. Siglec-2 / CD22 binds sialylated glycoproteins, one of which is CD45. Siglec2 / CD22 plays a role in positive regulation through interaction with Src family tyrosine kinases and may also act as an inhibitory receptor by recruiting cytoplasmic phosphatases via their SH2 domains that block signal transduction through dephosphorylation of signaling molecules.
Reconstitution Instructions: Reconstitute in sterile deionized water to a concentration of 50 μg/ml.
NCBI Gene Symbol: CD22
Gene ID: 12483
NCBI Accession: P35329-1
Additional Information
Size: |
50 μg |
Country of Manufacturing Origin: |
USA |
Country of Animal Origin: |
USA |
Gene Source: |
Mouse |
Recombinant: |
Yes |
Source: |
HEK293 cells |
Purity by SDS-PAGE: |
> 95% |
Assay: |
SDS-PAGE |
Purity: |
N/A |
Assay 2: |
N/A |
Endotoxin Level: |
< 1.0 EU per/μg |
Activity (Specifications/test method): |
N/A |
Biological activity: |
N/A |
Results: |
N/A |
Molecular Weight: |
78.3 kDa |
Storage Temperature: |
-20°C |
Shelf Life: |
12 months |
Concentration: |
N/A |
Appearance: |
Lyophilized |
Handling: |
Centrifuge the vial prior to opening. |