Human CellExp™ SARS-CoV-2 Spike RBD (N501Y), Recombinant

Human CellExp™ SARS-CoV-2 Spike RBD (N501Y), Recombinant is available at Gentaur for Next week delivery.

Spike RBD (N501Y) mutant increases binding affinity to ACE2

Biomolecule/Target:

Alternates names: COVID-19 Spike RBD protein (N501Y); 2019-nCoV Spike RBD protein (N501Y); SARS-CoV-2 Mutant (N501Y); SARS-CoV-2 (N501Y) mutant protein

Synonyms: COVID-19 Spike RBD protein (N501Y); 2019-nCoV Spike RBD protein (N501Y); SARS-CoV-2 Mutant (N501Y); SARS-CoV-2 (N501Y) mutant protein

Background Information: SARS-CoV-2 Spike protein is a large type I transmembrane protein composed of S1 subunit and S2 subunit. During viral infection, the receptor-binding domain (RBD) of the S1 subunit is responsible for the recognition and binding of host receptor ACE2, while the S2 subunit mediates viral cell membrane fusion. The SARS-CoV-2-S1-RBD/ACE2 interaction mediates viral entry into the target cells. The N501Y mutation in the receptor-binding domain (RBD) of SARS-CoV-2 variants increases binding affinity to ACE2.

Reconstitution Instructions:

NCBI Gene Symbol:

Gene ID:

NCBI Accession: QHD43416.1