Human CellExp™ SARS-CoV-2 Spike RBD (E484K)

Human CellExp™ SARS-CoV-2 Spike RBD (E484K) is available at Gentaur for Next week delivery.

Spike RBD variant with E84k mutation which mildly increase receptor binding

Biomolecule/Target:

Alternates names: COVID-19 Spike RBD protein (E484K); 2019-nCoV Spike RBD protein (E484K); SARS-CoV-2 Mutant (E484K); SARS-CoV-2 (E484K) mutant protein

Synonyms: COVID-19 Spike RBD protein (E484K); 2019-nCoV Spike RBD protein (E484K); SARS-CoV-2 Mutant (E484K); SARS-CoV-2 (E484K) mutant protein

Background Information: SARS-CoV-2 Spike protein is a large type I transmembrane protein composed of S1 subunit and S2 subunit. During viral infection, the receptor-binding domain (RBD) of the S1 subunit is responsible for the recognition and binding of host receptor ACE2, while the S2 subunit mediates viral cell membrane fusion. The SARS-CoV-2-S1-RBD/ACE2 interaction mediates viral entry into the target cells. The E484K mutant mildly increase receptor binding.

Reconstitution Instructions: Reconstitute in sterile water to a concentration of 1 mg/ml.

NCBI Gene Symbol:

Gene ID:

NCBI Accession: YP_009724390.1