Human CellExp™ SARS-CoV-2 Spike Protein (S1), Recombinant

Human CellExp™ SARS-CoV-2 Spike Protein (S1), Recombinant is available at Gentaur for Next week delivery.

Glycoprotein that enables viral entry into the host cell

Biomolecule/Target:

Alternates names: S1 protein, Spike glycoprotein Subunit1, S glycoprotein Subunit1, Spike protein S1, novel coronavirus s1 Protein

Synonyms: S1 protein, Spike glycoprotein Subunit1, S glycoprotein Subunit1, Spike protein S1, novel coronavirus s1 Protein

Background Information: SARS-CoV is an enveloped, single, and positive-stranded RNA virus. Cell entry of severe acute respiratory syndrome coronavirus (SARS-CoV) is mediated by the viral spike (S) protein. The spike (S) glycoprotein of coronaviruses is known to be essential in the binding of the virus to the host cell at the advent of the infection process. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. For viral entry, the surface unit (S1) of SARS S binds to the cellular receptor angiotensin-converting enzyme 2 (ACE2) and the transmembrane unit (S2) then fuses the viral membrane with a host cell membrane. The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity, during infection with SARS-CoV. Because the S protein of SARS-CoV is involved in receptor recognition, as well as virus attachment and entry, it represents one of the most important targets for the development of SARS vaccines and therapeutics.

Reconstitution Instructions: Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water.

NCBI Gene Symbol: S

Gene ID: 43740568

NCBI Accession: YP_009724390.1