Human CellExp™ Renin, Human Recombinant

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SKU:
6300-50
€185
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Description

Human CellExp™ Renin, Human Recombinant is available at Gentaur for Next week delivery.

An aspartyl protease specific for angiotensinogen.

Biomolecule/Target:

Alternates names: Angiotensinogenase, REN.

Synonyms: Angiotensinogenase, REN.

Background Information: Renin is a highly specific endopeptidase with the known function of generating angiotensin I from angiotensinogen in the plasma. This enzymatic reaction with the particular substrate angiotensinogen initiates a cascade of reactions that produce an elevation of blood pressure and increased sodium retention by the kidney. Prorenin is a glycosylated aspartic protease that consists of 2 homologous lobes and is the precursor of renin. Prorenin exhibits much lower level of enzymatic activity relative to activated renin. BioVision’s active human renin is produced from the pro-form prorenin by removing the 43 amino acid N-terminal pro-segment with trypsin

Reconstitution Instructions: N/A

NCBI Gene Symbol: REN

Gene ID: 5972

NCBI Accession: P00797

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Additional Information

Size:
50 μg
Adwords:
False
Country of Manufacturing Origin:
USA
Country of Animal Origin:
USA
Gene Source:
Human
Recombinant:
True
Source:
HEK 293 cells
Purity by SDS-PAGE:
≥95%
Assay:
SDS-PAGE
Purity:
N/A
Assay 2:
N/A
Endotoxin Level:
N/A
Activity (Specifications/test method):
The specific activity is > 20 U/mg. The specific activity of active Renin was assayed using BioVision’s Renin Activity Fluorometric Assay Kit (Catalog # K800).
Biological activity:
N/A
Results:
N/A
Molecular Weight:
43 kDa (C terminal 8×His tag)
Storage Temperature:
-20ºC
Shelf Life:
12 months
Appearance:
Lyophilized powder
Handling:
Centrifuge the vial prior to opening.
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