Human CellExp™ PVRIG, Fc Tag, Mouse recombinant

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SKU:
P1419-50
£135.37
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Description

Human CellExp™ PVRIG, Fc Tag, Mouse recombinant is available at Gentaur for Next week delivery.

acts as a coinhibitory receptor that suppresses T-cell receptor-mediated signals.

Biomolecule/Target:

Alternates names: Poliovirus Receptor-related Immunoglobulin Domain-containing Protein, C7orf15, CD112R, CD112 receptor, MGC104322, MGC138297, MGC2463

Synonyms: Poliovirus Receptor-related Immunoglobulin Domain-containing Protein, C7orf15, CD112R, CD112 receptor, MGC104322, MGC138297, MGC2463

Background Information: Human PVRIG (poliovirus receptor related immunoglobulin domain-containing protein), also known as CD112 receptor (CD112R), is an approximately 34 kDa single transmembrane protein in the poliovirus receptor-like protein (PVR) family. The CD112R gene encodes a putative single transmembrane protein, which is composed of a single extracellular IgV domain, one transmembrane domain, and a long intracellular domain. Notably, the intracellular domain of phatases. The extracellular domain sequence of human and mouse CD112R have 65.3% similarity. CD112R may act as a coinhibitory receptor that suppresses T-cell receptor-mediated signals.

Reconstitution Instructions: Reconstitute in sterile deionized water to a concentration of 100 µg/ml.

NCBI Gene Symbol:

Gene ID: 102640920

NCBI Accession: A0A1B0GS01

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Additional Information

Size:
50 μg
Adwords:
False
Country of Manufacturing Origin:
USA
Country of Animal Origin:
N/A
Gene Source:
Mouse
Recombinant:
False
Source:
HEK 293 Cells
Purity by SDS-PAGE:
>95%
Assay:
SDS-PAGE
Endotoxin Level:
Less than 1.0 EU per μg by the LAL method.
Molecular Weight:
This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 40.6 kDa. The protein migrates as 48-55 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Storage Temperature:
-20°C
Shelf Life:
12 months
Appearance:
Lyophilized powder
Handling:
Centrifuge the vial prior to opening.
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