BioVision Products
Human CellExp™ PD-1 /PDCD1, human recombinant
- SKU:
- 7498-50
Description
Human CellExp™ PD-1 /PDCD1, human recombinant is available at Gentaur for Next week delivery.
Inhibits the T-cell proliferation and production of IL-1, IL-4, IL-10 and IFN-? by suppressing the activation and transduction of PI3K/AKT pathway.
Biomolecule/Target: PD-1/PDCD1
Alternates names: PDCD1, PD1, CD279, SLEB2, hPD-1, hPD-l
Synonyms: PD, PD 1, PD 1 protein, PD 1 recombinant protein, human PD 1 protein, human recombinant PD 1 protein, human recombinant PD 1, human PD 1, recombinant PD 1, Human cell expressed PD 1, Human cell expressed PD 1 protein, Human cell expressed recombinant PD 1
Background Information: Programmed cell death 1 (PD1) is a cell surface membrane protein of the immunoglobulin superfamily. It is expressed on the surface of activated T cells, B cells, macrophages, myeloid cells and a subset of thymocytes. PD1 functions as an inhibitory cell su
Reconstitution Instructions: Centrifuge the vial prior to opening. Reconstitute in sterile PBS, pH 7.4 to a concentration of 50 µg/ml. Do not vortex. This solution can be stored at 2-8°C for up to 1 month. For extended storage, it is recommended to store at -20°C.
NCBI Gene Symbol: PDCD1
Gene ID: 5133
NCBI Accession: Q15116
Additional Information
Size: |
50 μg |
Country of Manufacturing Origin: |
USA |
Country of Animal Origin: |
USA |
Gene Source: |
Human |
Recombinant: |
Yes |
Source: |
HEK293 cells |
Purity by SDS-PAGE: |
?95% |
Assay: |
SDS-PAGE |
Purity: |
N/A |
Assay 2: |
N/A |
Endotoxin Level: |
N/A |
Activity (Specifications/test method): |
Measured by its binding ability in a functional ELISA |
Biological activity: |
Immobilized Human PD-1, His Tag at 5?g/mL (100 ?L/well) can bind Human PD-L1, His Tag with a linear range of 0.15-1.25 ?g/mL |
Results: |
N/A |
Molecular Weight: |
This protein is fused with a polyhistidine tag at the C-terminus, and has a calculated MW of 17.2 kDa. The predicted N-terminus is Leu 25. DTT-reduced Protein migrates as 25-40 kDa in SDS-PAGE due to glycosylation. |
Storage Temperature: |
-20°C |
Shelf Life: |
12 months |
Concentration: |
N/A |
Appearance: |
Lyophilized |
Handling: |
Centrifuge the vial prior to opening. |