BioVision Proteins
Human CellExp™ NOV, human recombinant
- SKU:
- P1022-25
Description
Human CellExp™ NOV, human recombinant is available at Gentaur for Next week delivery.
Biomolecule/Target: NOV
Alternates names: Nephroblastoma Overexpressed gene, CCN3, IGFBP9, NovH
Synonyms: Nephroblastoma Overexpressed gene, CCN3, IGFBP9, NovH
Background Information: Nephroblastoma Overexpressed Gene Protein (NOV), also known as CCN3, IGFBP9 and NOVH, is one of the CCN family of secreted proteins. It is expressed in bone marrow, thymic cells and nephroblastoma. NOV signals through integrin receptors, NOTCH1 and fibulin 1c to regulate multiple cellular activities, such as cell adhesion, migration, proliferation and differentiation. The reported functions of NOV are diverse. It has been reported to play a role in angiogenesis and stem cell self-renewal. It has also been implicated in osteogenic differentiation, embryo development and cancer pathogenesis.
Reconstitution Instructions: Reconstituted in ddH2O at 100 μg/mL.
NCBI Gene Symbol: NOV
Gene ID: 4856
NCBI Accession: P48745
Additional Information
Size: |
25 µg |
Country of Manufacturing Origin: |
USA |
Country of Animal Origin: |
USA |
Gene Source: |
Human |
Recombinant: |
Yes |
Source: |
CHO cells |
Purity by SDS-PAGE: |
> 95% |
Assay: |
SDS-PAGE |
Purity: |
> 95% |
Assay 2: |
HPLC |
Endotoxin Level: |
< 0.2 EU/μg |
Activity (Specifications/test method): |
Prolifiration assay |
Biological activity: |
ED50 <5 μg/ml, measured in a cell proliferation assay using 3T3 cells. |
Results: |
N/A |
Molecular Weight: |
20-50 kDa |
Storage Temperature: |
-20°C |
Shelf Life: |
12 months |
Concentration: |
N/A |
Appearance: |
Lyophilized |
Handling: |
Centrifuge the vial prior to opening. |