Human CellExp™ NOV, human recombinant

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SKU:
P1022-25
€185
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Description

Human CellExp™ NOV, human recombinant is available at Gentaur for Next week delivery.

Biomolecule/Target: NOV

Alternates names: Nephroblastoma Overexpressed gene, CCN3, IGFBP9, NovH

Synonyms: Nephroblastoma Overexpressed gene, CCN3, IGFBP9, NovH

Background Information: Nephroblastoma Overexpressed Gene Protein (NOV), also known as CCN3, IGFBP9 and NOVH, is one of the CCN family of secreted proteins. It is expressed in bone marrow, thymic cells and nephroblastoma. NOV signals through integrin receptors, NOTCH1 and fibulin 1c to regulate multiple cellular activities, such as cell adhesion, migration, proliferation and differentiation. The reported functions of NOV are diverse. It has been reported to play a role in angiogenesis and stem cell self-renewal. It has also been implicated in osteogenic differentiation, embryo development and cancer pathogenesis.

Reconstitution Instructions: Reconstituted in ddH2O at 100 μg/mL.

NCBI Gene Symbol: NOV

Gene ID: 4856

NCBI Accession: P48745

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Additional Information

Size:
25 µg
Country of Manufacturing Origin:
USA
Country of Animal Origin:
USA
Gene Source:
Human
Recombinant:
Yes
Source:
CHO cells
Purity by SDS-PAGE:
> 95%
Assay:
SDS-PAGE
Purity:
> 95%
Assay 2:
HPLC
Endotoxin Level:
< 0.2 EU/μg
Activity (Specifications/test method):
Prolifiration assay
Biological activity:
ED50 <5 μg/ml, measured in a cell proliferation assay using 3T3 cells.
Results:
N/A
Molecular Weight:
20-50 kDa
Storage Temperature:
-20°C
Shelf Life:
12 months
Concentration:
N/A
Appearance:
Lyophilized
Handling:
Centrifuge the vial prior to opening.
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