Human CellExp™ MMP-9, human recombinant

Human CellExp™ MMP-9, human recombinant is available at Gentaur for Next week delivery.

Involved in the breakdown of extracellular matrix

Biomolecule/Target: MMP-9

Alternates names: MMP9, CLG4B, GELB, MANDP2, MMP-9, Matrix Metalloproteinase-9

Synonyms: MMP9, CLG4B, GELB, MANDP2, MMP-9, Matrix Metalloproteinase-9

Background Information: Matrix metallopeptidase 9 (MMP-9) is secreted from neutrophils, macrophages and a number of transformed cells. It is the most complex MMP family member in terms of domain structure and regulation of its activity. MMP family is involved in the breakdown of extracellular matrix in normal physiological processes as well as in disease processes. Most MMPs are secreted as inactive pro-proteins which are activated by the cleavage of extracellular proteinases. MMP-9 degrades various substrates including gelatin, collagen types IV and V, and elastin. It is involved in inflammatory responses, tissue remodeling, wound healing, tumor growth and diseases including systemic lupus erythematosus, rheumatoid arthritis, and multiple sclerosis. MMP-9 is regarded as a potential therapeutic target and a biomarker of disease status.

Reconstitution Instructions: Centrifuge the vial prior to opening. Reconstitute in sterile PBS (pH 7.4). Do not vortex.

NCBI Gene Symbol: MMP-9

Gene ID: 4318

NCBI Accession: P14780