BioVision Products
Human CellExp™ IL20RB /IL-20R2, human recombinant
- SKU:
- 7447-50
Description
Human CellExp™ IL20RB /IL-20R2, human recombinant is available at Gentaur for Next week delivery.
A receptor for IL19, IL20 and IL24
Biomolecule/Target: IL20RB /IL-20R2
Alternates names: IL20RB, IL-20R2, IL-20R-beta, DIRS1, FNDC6
Synonyms: IL20RB, IL-20R2, IL-20R-beta, DIRS1, FNDC6
Background Information: Interleukin-20 receptor subunit beta (IL20RB) is also known as IL-20R2, DIRS1, which belongs to the type II cytokine receptor family. IL20RB / IL-20R2 contains two fibronectin type-III domains. IL20RB / IL-20R2 is widely expressed with highest levels in skin and testis. IL20RB can be fused with IL20RA or IL22RA1 forming heterodimer. The IL20RA/IL20RB dimer is a receptor for IL19, IL20 and IL24. The IL22RA1/IL20RB dimer is a receptor for IL20 and IL24.
Reconstitution Instructions: Centrifuge the vial prior to opening. Reconstitute in sterile PBS, pH 7.4 to a concentration of 50 µg/ml. Do not vortex. This solution can be stored at 2-8°C for up to 1 month. For extended storage, it is recommended to store at -20°C.
NCBI Gene Symbol: IL20RB
Gene ID: 53833
NCBI Accession: Q6UXL0
Additional Information
Size: |
50 μg |
Country of Manufacturing Origin: |
USA |
Country of Animal Origin: |
USA |
Gene Source: |
Human |
Recombinant: |
Yes |
Source: |
HEK293 cells |
Purity by SDS-PAGE: |
≥90% |
Assay: |
SDS-PAGE |
Purity: |
N/A |
Assay 2: |
N/A |
Endotoxin Level: |
<1 EU/μg by LAL method |
Activity (Specifications/test method): |
N/A |
Biological activity: |
Measured by its binding ability in a functional ELISA. When Recombinant Human IL‑19 protein is present at 0.2 µg/mL, the concentration of rhIL20RB Fc Chimera that produces 50% of the optimal binding response is approximately 5‑50 ng/ml. |
Results: |
Measured by its binding ability in a functional ELISA. When Recombinant Human IL‑19 protein is present at 0.2 µg/mL, the concentration of rhIL20RB Fc Chimera that produces 50% of the optimal binding response is approximately 5‑50 ng/ml. |
Molecular Weight: |
This protein fused with Fc fragment of human IgG1 at the C-terminus, has a calculated MW of 49.1 kDa. The predicted N-terminus is Asp 30. As a result of glycosylation, DTT-reduced Protein migrates as 50 kDa and non-reduced protein migrates as 100 kDa |
Storage Temperature: |
-20°C |
Shelf Life: |
12 months |
Concentration: |
N/A |
Appearance: |
Lyophilized |
Handling: |
Centrifuge the vial prior to opening. |