Human CellExp™ IL-28B, Human Recombinant

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SKU:
6472-50
€185
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Description

Human CellExp™ IL-28B, Human Recombinant is available at Gentaur for Next week delivery.

A cytokine mediating adaptive immune response

Biomolecule/Target:

Alternates names: Interleukin-28A, IL-28A, IFN-Lambda 2, Interferon-Lambda 2, Cytokine ZCYTO20, IL28A, IFNL2, ZCYTO20.

Synonyms: Human Cellexp Human Recombinant IL-28B

Background Information: IL-28B is a cytokine remotely related to type I interferons and the IL-10 family. Interleukin-28B, interleukin 28A (IL28A), and interleukin 29 (IL29) are 3 closely related cytokine genes which form a cytokine gene cluster on a chromosomal region mapped to 19q13. Expression of the cytokines encoded by these 3 genes can be induced by viral infection. All 3 cytokines interact with a heterodimeric class II cytokine receptor which consists of interleukin 10 receptor, beta (IL10RB) and interleukin 28 receptor, alpha (IL28RA).

Reconstitution Instructions: Reconstitute in sterile PBS containing 0.1% endotoxin-free recombinant human serum albumin.

NCBI Gene Symbol: IFNL3

Gene ID: 282617

NCBI Accession: Q8IZI9

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Additional Information

Size:
50 µg
Country of Manufacturing Origin:
USA
Country of Animal Origin:
China
Gene Source:
Human
Recombinant:
Yes
Source:
Human 293 cell expressed
Purity by SDS-PAGE:
> 95%
Assay:
SDS-PAGE
Purity:
N/A
Assay 2:
N/A
Endotoxin Level:
< 1.0 EU per 1 μg of protein
Activity (Specifications/test method):
N/A
Biological activity:
ED₅₀ is typically 0.1 to 1 ng/mL. The specific activity was determined by the dose-dependent protection of the cytopathic effect on A549 cells (human lung adenocarcinoma epithelial cell line) that were challenged with encephalomyocarditis (EMC) virus
Results:
0.1 to 1 ng/ml
Molecular Weight:
24 kDa, monomer, non-glycosylated
Storage Temperature:
-20°C
Shelf Life:
12 months
Concentration:
N/A
Appearance:
Lyophilized
Handling:
Centrifuge the vial prior to opening.
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