Human CellExp™ IL-2 R beta /CD122, human recombinant

Human CellExp™ IL-2 R beta /CD122, human recombinant is available at Gentaur for Next week delivery.

Involved in receptor mediated endocytosis

Biomolecule/Target: IL-2 R beta /CD122

Alternates names: IL2RB, RP5-1170K4.6, CD122, P70-75

Synonyms: IL2RB, RP5-1170K4.6, CD122, P70-75

Background Information: Interleukin-2 receptor (IL-2R) is a heterotrimeric protein expressed on the surface of certain immune cells, such as lymphocytes, that binds and responds to a cytokine called IL-2. The IL-2R is made up of 3 subunits - α (CD25), β (CD122) and γ (CD132) - non-covalently associating. The α and β chains are involved in binding IL-2, while signal transduction following cytokine interaction is carried out by the γ-chain, along with the β subunit. CD122 also known as IL2R beta, is a member of the type I cytokine receptor family. CD122 is the receptor for interleukin-2 and is involved in receptor mediated endocytosis and transduces the mitogenic signals of IL2.

Reconstitution Instructions: Centrifuge the vial prior to opening. Reconstitute in sterile PBS, pH 7.4 to a concentration of 50 µg/ml. Do not vortex. This solution can be stored at 2-8°C for up to 1 month. For extended storage, it is recommended to store at -20°C.

NCBI Gene Symbol: IL2RB

Gene ID: 3560

NCBI Accession: P14784