Human CellExp™ Hyaluronidase 1/HYAL1, Human Recombinant

Human CellExp™ Hyaluronidase 1/HYAL1, Human Recombinant is available at Gentaur for Next week delivery.

Play a role in promoting tumor progression

Biomolecule/Target:

Alternates names: Hyaluronidase-1, Hyal-1,Hyaluronoglucosaminidase-1, Lung carcinoma protein 1, LuCa-1, HYAL1, Hyaluronidase 1, Hyaluronoglucosaminidase 1, Hyaluronoglucosaminidase1, LUCA 1,MPS9, NAT6, Plasma hyaluronidase, Tumor suppressor LUCA 1

Synonyms: Hyaluronidase-1, Hyal-1,Hyaluronoglucosaminidase-1, Lung carcinoma protein 1, LuCa-1, HYAL1, Hyaluronidase 1, Hyaluronoglucosaminidase 1, Hyaluronoglucosaminidase1, LUCA 1,MPS9, NAT6, Plasma hyaluronidase, Tumor suppressor LUCA 1

Background Information: HYAL1, also known as Hyaluronidase-1, is a member of the endolytic glycoside hydrolase family. Human hyaluronidases (HYALs) are a group of five endo¬β¬N¬acetyl¬hexosaminidases that include HYAL1, HYAL2, HYAL3, HYAL4, and SPAM1 (PH20). HYAL1 preferentially degrades hyaluronic acid present in the extracellular matrix of somatic tissues. This protein is active at an acidic pH and is the major hyaluronidase in plasma. Defects in HYAL1 are associated with mucopolysaccharidosis type IX, or hyaluronidase deficiency. It is implicated in several types of cancers, likely due to the angiogenic effects of HYAL1-cleaved hyaluronan fragments. Recombinant human HYAL1, fused to His-tag at C-terminus, was expressed in HEK293 cell and purified by using conventional chromatography techniques.

Reconstitution Instructions:

NCBI Gene Symbol: HYAL1

Gene ID: 3373

NCBI Accession: Q12794