BioVision Proteins
Human CellExp™ Human CD40/ TNFRSF5, Human recombinant
- SKU:
- 9230-50
Description
Human CellExp™ Human CD40/ TNFRSF5, Human recombinant is available at Gentaur for Next week delivery.
Tumor necrosis factor receptor superfamily member 5
Biomolecule/Target: CD41
Alternates names: CD40, Bp50, CDW40, MGC9013, TNFRSF5, p51
Synonyms: CD40, Bp50, CDW40, MGC9013, TNFRSF5, p51
Background Information: Tumor necrosis factor receptor superfamily member 5 (TNFRSF5) is also known as CD40, is a member of the TNF receptor superfamily. The expression of CD40 is diverse. TNFRSF5 has been found to be essential in mediating a broad variety of immune and inflammatory responses including T cell-dependent immunoglobulin class switching, memory B cell development, and germinal center formation. CD40 is the receptor for TNFSF5/CD40LG. Defects in CD40 are the cause of immunodeficiency with hyper-IgM type 3 (HIGM3).
Reconstitution Instructions: Reconstitute in sterile PBS, pH 7.4 to a concentration of 50 μg/ml
NCBI Gene Symbol: CD40
Gene ID: 958
NCBI Accession: AAH12419.2
Additional Information
Size: |
50 µg |
Country of Manufacturing Origin: |
USA |
Country of Animal Origin: |
USA |
Gene Source: |
Human |
Recombinant: |
Yes |
Source: |
HEK 293 cells |
Purity by SDS-PAGE: |
>95% |
Assay: |
SDS-PAGE |
Purity: |
>95% |
Assay 2: |
N/A |
Endotoxin Level: |
< 1 EU/μg |
Activity (Specifications/test method): |
Measured by its binding ability in a functional ELISA. |
Biological activity: |
Immobilized Human CD40, His Tag at 1 µg/mL (100 µL/well) can bind Human CD40 Ligand /TNFSF5 with a linear range of 0.01-0.12 ng/mL. |
Results: |
N/A |
Molecular Weight: |
This protein is fused with a 6× His tag at C-terminus and has a calculated MW of 20 kDa. The protein migrates as 32 kDa in SDS-PAGE due to glycosylation. |
Storage Temperature: |
-20°C |
Shelf Life: |
12 months |
Concentration: |
N/A |
Appearance: |
Lyophilized |
Handling: |
Centrifuge the vial prior to opening. |