Human CellExp™ Frizzled-7 / FZD7 Protein, Human recombinant

Human CellExp™ Frizzled-7 / FZD7 Protein, Human recombinant is available at Gentaur for Next week delivery.

Biomolecule/Target: FZD7

Alternates names: FZD7, Frizzled-7, FzE3, Fz-7, hFz8

Synonyms: FZD7, Frizzled-7, FzE3, Fz-7, hFz7

Background Information: Frizzled-7 (FZD7) is also known as FzE3, which belongs to the G-protein coupled receptor Fz/Smo family. Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. FZD7 contains one FZ (frizzled) domain. FZD7 is receptor for Wnt proteins. FZD7 may be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues. FZD7 interacts with MAGI3 and DVL1.

Reconstitution Instructions: Centrifuge the vial prior to opening. Reconstitute in sterile PBS, pH 7.4 to a concentration of 50 µg/ml. Do not vortex.

NCBI Gene Symbol: FZD7

Gene ID: 8324

NCBI Accession: O75084