Human CellExp™ Frizzled-5 / FZD5 Protein, Human recombinant

Human CellExp™ Frizzled-5 / FZD5 Protein, Human recombinant is available at Gentaur for Next week delivery.

Biomolecule/Target: FZD5

Alternates names:

Synonyms: FZD5, Frizzled-5, C2orf31, Fz-5, hFz5, FzE5

Background Information: Frizzled‐5 (FZD5) is also known as FzE5, which belongs to the G‐protein coupled receptor Fz/Smo family. Most of frizzled receptors are coupled to the beta‐catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK‐3 kinase, nuclear accumulation of beta‐catenin and activation of Wnt target genes. FZD5 contains one FZ (frizzled) domain. FZD5 may be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues. FZD5 interacts specifically with Wnt5A to induce the beta‐catenin pathway. FZD5 interacts with GOPC.

Reconstitution Instructions: Centrifuge the vial prior to opening. Reconstitute in sterile PBS, pH 7.4 to a concentration of 50 µg/ml. Do not vortex.

NCBI Gene Symbol: FZD5

Gene ID: 7855

NCBI Accession: Q13467