BioVision Products
Human CellExp™ FGF-7 (KGF), Human Recombinant
- SKU:
- 6450-50
Description
Human CellExp™ FGF-7 (KGF), Human Recombinant is available at Gentaur for Next week delivery.
A potent mitogen for keratinocytes and epithelial cells
Biomolecule/Target:
Alternates names: HBGF-7, FGF7, FGF-7, KGF
Synonyms: Human Cellexp Human Recombinant FGF-7 (KGF)
Background Information: FGF-7 is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. FGF7 is a potent epithelial cell-specific growth factor, whose mitogenic activity is predominantly exhibited in keratinocytes but not in fibroblasts and endothelial cells. Studies of mouse and rat homologs of this gene implicated roles in morphogenesis of epithelium, reepithelialization of wounds, hair development and early lung organogenesis.
Reconstitution Instructions: Reconstitute in sterile PBS containing 0.1% endotoxin-free, recombinant human serum albumin.
NCBI Gene Symbol: FGF7
Gene ID: 2252
NCBI Accession: P21781
Additional Information
Size: |
50 μg |
Country of Manufacturing Origin: |
USA |
Country of Animal Origin: |
USA |
Gene Source: |
Human |
Recombinant: |
Yes |
Source: |
Human cell expressed |
Purity by SDS-PAGE: |
≥95% |
Assay: |
SDS-PAGE |
Purity: |
N/A |
Assay 2: |
N/A |
Endotoxin Level: |
< 1.0 EU per 1 μg of protein |
Activity (Specifications/test method): |
N/A |
Biological activity: |
ED₅₀ is typically 1.5 to 7.5 ng/mL. The specific activity was determined by the Dose-dependent stimulation of the proliferation of 4MBr-5 cells (monkey epithelial cell line). |
Results: |
1.5 to 7.5 ng/ml |
Molecular Weight: |
17 and 30 kDa, monomer, glycosylated |
Storage Temperature: |
-20°C |
Shelf Life: |
12 months |
Concentration: |
N/A |
Appearance: |
Lyophilized |
Handling: |
Centrifuge the vial prior to opening. |