Human CellExp™ Coronavirus Spike Protein (SARS-CoV-2), Recombinant

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SKU:
P1547-50
£135.37
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Description

Human CellExp™ Coronavirus Spike Protein (SARS-CoV-2), Recombinant is available at Gentaur for Next week delivery.

Glycoprotein that enables viral entry into the host cell

Biomolecule/Target:

Alternates names:

Synonyms:

Background Information: SARS-CoV is an enveloped, single and positive-stranded RNA virus. Cell entry of severe acute respiratory syndrome coronavirus (SARS-CoV) is mediated by the viral spike (S) protein. The spike (S) glycoprotein of coronaviruses is known to be essential in the binding of the virus to the host cell at the advent of the infection process. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. For viral entry, the surface unit (S1) of SARS S binds to the cellular receptor angiotensin-converting enzyme 2 (ACE2) and the transmembrane unit (S2) then fuses the viral membrane with a host cell membrane. The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity, during infection with SARS-CoV. Because the S protein of SARS-CoV is involved in receptor recognition, as well as virus attachment and entry, it represents one of the most important targets for the development of SARS vaccines and therapeutics.

Reconstitution Instructions:

NCBI Gene Symbol: S

Gene ID:

NCBI Accession: P0DTC2

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Additional Information

Size:
50 μg
Adwords:
FAUX
Country of Manufacturing Origin:
USA
Country of Animal Origin:
USA
Gene Source:
Coronavirus
Recombinant:
FAUX
Source:
HEK 293 cells
Purity by SDS-PAGE:
>90%
Molecular Weight:
138 kDa (His tag)
Storage Temperature:
-70 °C
Shelf Life:
12 months
Appearance:
Liquid protein
Handling:
Centrifuge the vial prior to opening.
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