BioVision Proteins
Human CellExp™ Complement Factor D, Human Recombinant
- SKU:
- P1491-10
Description
Human CellExp™ Complement Factor D, Human Recombinant is available at Gentaur for Next week delivery.
Serine protease that stimulates glucose transport, inhibits lipolysis
Biomolecule/Target:
Alternates names: CFD, Adipsin, PFD, DF, Complement factor D
Synonyms: CFD, Adipsin, PFD, DF, Complement factor D
Background Information: Complement factor D (CFD) is also known as Adipsin, C3 convertase activator, Properdin factor D (PFD), which contains one peptidase S1 domain and belongs to the peptidase S1 family. CFD / Adipsin cleaves factor B when the latter is complexed with factor C3b, activating the C3bbb complex, which then becomes the C3 convertase of the alternate pathway. CFD / Adipsin is a serine protease that stimulates glucose transport for triglyceride accumulation in fats cells and inhibits lipolysis. Defects in CFD / Adipsin are the cause of complement factor D deficiency which predisposes to invasive meningococcal disease.
Reconstitution Instructions: Reconstitute in sterile deionized water to the desired protein concentration.
NCBI Gene Symbol: CFD
Gene ID: 1675
NCBI Accession: P00746-1
Additional Information
Size: |
10 µg |
Adwords: |
False |
Country of Manufacturing Origin: |
USA |
Country of Animal Origin: |
USA |
Gene Source: |
Human |
Recombinant: |
True |
Source: |
HEK 293 cells |
Purity by SDS-PAGE: |
>90% |
Endotoxin Level: |
Less than 1.0 EU per μg by the LAL method. |
Molecular Weight: |
This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 26.3 kDa. The protein migrates as 28 kDa under non-reducing (NR) condition (SDS-PAGE) due to glycosylation. |
Storage Temperature: |
-20°C |
Shelf Life: |
12 months |
Appearance: |
Lyophilized powder |
Handling: |
Centrifuge the vial prior to opening. |