Human CellExp™ Complement Factor D, Human Recombinant

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SKU:
P1491-10
€185
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Description

Human CellExp™ Complement Factor D, Human Recombinant is available at Gentaur for Next week delivery.

Serine protease that stimulates glucose transport, inhibits lipolysis

Biomolecule/Target:

Alternates names: CFD, Adipsin, PFD, DF, Complement factor D

Synonyms: CFD, Adipsin, PFD, DF, Complement factor D

Background Information: Complement factor D (CFD) is also known as Adipsin, C3 convertase activator, Properdin factor D (PFD), which contains one peptidase S1 domain and belongs to the peptidase S1 family. CFD / Adipsin cleaves factor B when the latter is complexed with factor C3b, activating the C3bbb complex, which then becomes the C3 convertase of the alternate pathway. CFD / Adipsin is a serine protease that stimulates glucose transport for triglyceride accumulation in fats cells and inhibits lipolysis. Defects in CFD / Adipsin are the cause of complement factor D deficiency which predisposes to invasive meningococcal disease.

Reconstitution Instructions: Reconstitute in sterile deionized water to the desired protein concentration.

NCBI Gene Symbol: CFD

Gene ID: 1675

NCBI Accession: P00746-1

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Additional Information

Size:
10 µg
Adwords:
False
Country of Manufacturing Origin:
USA
Country of Animal Origin:
USA
Gene Source:
Human
Recombinant:
True
Source:
HEK 293 cells
Purity by SDS-PAGE:
>90%
Endotoxin Level:
Less than 1.0 EU per μg by the LAL method.
Molecular Weight:
This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 26.3 kDa. The protein migrates as 28 kDa under non-reducing (NR) condition (SDS-PAGE) due to glycosylation.
Storage Temperature:
-20°C
Shelf Life:
12 months
Appearance:
Lyophilized powder
Handling:
Centrifuge the vial prior to opening.
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