Human CellExp™ CD47, Rhesus macaque Recombinant

Human CellExp™ CD47, Rhesus macaque Recombinant is available at Gentaur for Next week delivery.

Plays a role in cell adhesion modulation of integrins

Biomolecule/Target: CD47

Alternates names: CD47, MER6, IAP, OA3

Synonyms: CD47, MER6, IAP, OA3

Background Information: Leukocyte surface antigen CD47 is also known as Antigenic surface determinant protein OA3, Integrin-associated protein (IAP) and Protein MER6. CD47 contains 1 Ig-like V-type (immunoglobulin-like) domain. CD47 is very broadly distributed on normal adult tissues. CD47 has a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins and plays an important role in memory formation and synaptic plasticity in the hippocampus by similarity. CD47 is the receptor for SIRPA, binding to which prevents maturation of immature dendritic cells and inhibits cytokine production by mature dendritic cells. CD47 Interaction with SIRPG mediates cell-cell adhesion, enhances superantigen-dependent T-cell-mediated proliferation and costimulates T-cell activation.

Reconstitution Instructions: Reconstitute in sterile deionized water to a concentration of 50 µg/ml.

NCBI Gene Symbol: CD47

Gene ID: 704980

NCBI Accession: F7A802