Human CellExp™ CD45, human recombinant

Human CellExp™ CD45, human recombinant is available at Gentaur for Next week delivery.

Receptor-type tyrosine-protein phosphatase C

Biomolecule/Target: PTPRC

Alternates names: LCA; LY5; B220; T200; CD45R; GP180; PTPRC

Synonyms: LCA; LY5; B220; T200; CD45R; GP180; PTPRC

Background Information: Protein tyrosine phosphatase, receptor type C (CD45), also known as PTPRC is a member of the protein tyrosine phosphatase (PTP) family which is known for its function to serve as signaling molecules and to regulate a variety of cellular processes such as cell proliferation, differentiation, mitotic cycle and oncogenic transformation. CD45 is found expression specifically in hemotopietic cells. CD45 consists of an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains. It serves as an essential regulator of T-cell and B-cell antigen receptor signaling through either direct interaction with components of the antigen receptor complexs or by activating various Src family kinases required for the antigen receptor signaling and it also can suppress JAK kinases.

Reconstitution Instructions: Reconstitute in 1X PBS to the desired protein concentration.

NCBI Gene Symbol: PTPRC

Gene ID: 5788

NCBI Accession: P08575