BioVision Products
Human CellExp™ CD306 / LAIR2, human recombinant
- SKU:
- 7377-50
Description
Human CellExp™ CD306 / LAIR2, human recombinant is available at Gentaur for Next week delivery.
Plays a potential role in modulating mucosal tolerance
Biomolecule/Target: CD306/LAIR2
Alternates names: LAIR2, CD306
Synonyms: LAIR2, CD306
Background Information: Leukocyte-associated immunoglobulin-like receptor 2 (LAIR2) is also known as CD antigen CD306. LAIR2 contains one Ig-like C2-type (immunoglobulin-like) domain. LAIR2 is a member of the immunoglobulin superfamily and was identified by its similarity to LAIR1, an inhibitory receptor present on mononuclear leukocytes. LAIR2 / CD306 is thought to be secreted and may help modulate mucosal tolerance.
Reconstitution Instructions: Centrifuge the vial prior to opening. Reconstitute in sterile PBS, pH 7.4 to a concentration of 50 µg/ml. Do not vortex. This solution can be stored at 2-8°C for up to 1 month. For extended storage, it is recommended to store at -20°C.
NCBI Gene Symbol: LAIR2
Gene ID: 3904
NCBI Accession: Q6ISS4
Additional Information
Size: |
50 μg |
Country of Manufacturing Origin: |
USA |
Country of Animal Origin: |
USA |
Gene Source: |
Human |
Recombinant: |
Yes |
Source: |
HEK293 cells |
Purity by SDS-PAGE: |
≥95% |
Assay: |
SDS-PAGE |
Purity: |
N/A |
Assay 2: |
N/A |
Endotoxin Level: |
<1 EU/μg by LAL method |
Activity (Specifications/test method): |
N/A |
Biological activity: |
Measured by the ability of the immobilized protein to support the adhesion of HT-29 human colon adenocarcinoma cells. When 10000 cells/well are added to rhLAIR2 /CD306 coated plates (50 μg/ml with 100 μl/well), approximately >40% cells will adhere af |
Results: |
Measured by the ability of the immobilized protein to support the adhesion of HT-29 human colon adenocarcinoma cells. When 10000 cells/well are added to rhLAIR2 /CD306 coated plates (50 μg/ml with 100 μl/well), approximately >40% cells will adhere af |
Molecular Weight: |
This protein is fused with 6×His tag at the C-terminus, has a calculated MW of 14.9 kDa. The predicted N-terminus is Gln 22. DTT-reduced Protein migrates as 19-23 kDa. |
Storage Temperature: |
-20°C |
Shelf Life: |
12 months |
Concentration: |
N/A |
Appearance: |
Lyophilized |
Handling: |
Centrifuge the vial prior to opening. |