Human CellExp™ CD244/ 2B4/ SLAMF4, Fc Tag, Human Recombinant

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SKU:
P1305-50
€185
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Description

Human CellExp™ CD244/ 2B4/ SLAMF4, Fc Tag, Human Recombinant is available at Gentaur for Next week delivery.

Modulates receptor-ligand interactions to enhance leukocyte activation

Biomolecule/Target: CD244

Alternates names: CD244, 2B4, SLAMF4, NKR2B4, NAIL, h2B4

Synonyms: CD244, 2B4, SLAMF4, NKR2B4, NAIL, h2B4

Background Information: Natural killer cell receptor 2B4 is also known as NK cell type I receptor protein 2B4 (NKR2B4 or h2B4), SLAM family member 4 (SLAMF4), Signaling lymphocytic activation molecule 4, CD antigen CD244. NKR2B4 / CD244 contain two Ig-like (immunoglobulin-like) domains. CD244 is expressed in spleen, PBL, followed by lung, liver, testis and small intestine. CD244 interacts with CD48. Following phosphorylation, CD244 is able to recruit PTPN11/SHP-2 and SH2D1A/SAP. SLAMF4 modulate other receptor-ligand interactions to enhance leukocyte activation. CD244/2B4 is the only heterophilic receptor of SLAM family.

Reconstitution Instructions: Reconstitute in sterile deionized water to a concentration of 50 µg/ml.

NCBI Gene Symbol: CD244

Gene ID: 51744

NCBI Accession: Q9BZW8

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Additional Information

Size:
50 μg
Country of Manufacturing Origin:
USA
Country of Animal Origin:
USA
Gene Source:
Human
Recombinant:
Yes
Source:
HEK293 cells
Purity by SDS-PAGE:
≥95%
Assay:
SDS-PAGE
Purity:
N/A
Assay 2:
N/A
Endotoxin Level:
<1 EU/μg by LAL method
Activity (Specifications/test method):
Measured by its binding ability in a functional ELISA.
Biological activity:
Immobilized Human CD48, His Tag at 5 μg/mL (100 μL/well) can bind Human 2B4, Fc Tag with a linear range of 0.313-5 μg/mL.
Results:
N/A
Molecular Weight:
48.9 kDa
Storage Temperature:
-20°C
Shelf Life:
12 months
Concentration:
N/A
Appearance:
Lyophilized
Handling:
Centrifuge the vial prior to opening.
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