BioVision Products
Human CellExp™ CD166/ ALCAM, human recombinant
- SKU:
- 7437-50
Description
Human CellExp™ CD166/ ALCAM, human recombinant is available at Gentaur for Next week delivery.
A cell adhesion molecule that binds to CD6
Biomolecule/Target: CD166/ ALCAM
Alternates names: CD166, ALCAM, CD6L, KG-CAM, MEMD
Synonyms: CD166, ALCAM, CD6L, KG-CAM, MEMD
Background Information: CD166 antigen is a 100-105 kDa type I transmembrane glycoprotein that is a member of the immunoglobulin superfamily of proteins, which is also known as activated leukocyte cell adhesion molecule (ALCAM) in human, SC-1/DM-GRASP/BEN in the chicken, and KG-CAM in the rat. CD166 is a cell adhesion molecule that binds to CD6. CD166 involved in neurite extension by neurons via heterophilic and homophilic interactions.
Reconstitution Instructions: Centrifuge the vial prior to opening. Reconstitute in sterile PBS, pH 7.4 to a concentration of 50 µg/ml. Do not vortex. This solution can be stored at 2-8°C for up to 1 month. For extended storage, it is recommended to store at -20°C.
NCBI Gene Symbol: ALCAM
Gene ID: 214
NCBI Accession: Q13740
Additional Information
Size: |
50 μg |
Country of Manufacturing Origin: |
USA |
Country of Animal Origin: |
USA |
Gene Source: |
Human |
Recombinant: |
Yes |
Source: |
HEK293 cells |
Purity by SDS-PAGE: |
≥95% |
Assay: |
SDS-PAGE |
Purity: |
N/A |
Assay 2: |
N/A |
Endotoxin Level: |
<1 EU/μg by LAL method |
Activity (Specifications/test method): |
N/A |
Biological activity: |
Measured by its binding ability in a functional ELISA. Immobilized rh CD166 / ALCAM at 10 μg/ml (100 μl/well) can bind mouse CD6 Fc Chimera. The EC50 of mouse CD6 Fc Chimera is 0.1-0.22 μg/ml. |
Results: |
Measured by its binding ability in a functional ELISA. Immobilized rh CD166 / ALCAM at 10 μg/ml (100 μl/well) can bind mouse CD6 Fc Chimera. The EC50 of mouse CD6 Fc Chimera is 0.1-0.22 μg/ml. |
Molecular Weight: |
This protein is fused with 6×his tag at the C-terminus, and has a calculated MW of 56.8 kDa. The predicted N-terminus is Trp 28. DTT-reduced Protein migrates as 65-80 kDa in SDS-PAGE due to glycosylation. |
Storage Temperature: |
-20°C |
Shelf Life: |
12 months |
Concentration: |
N/A |
Appearance: |
Lyophilized |
Handling: |
Centrifuge the vial prior to opening. |